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Calcium Induced Regulation of Skeletal Troponin — Computational Insights from Molecular Dynamics Simulations

The interaction between calcium and the regulatory site(s) of striated muscle regulatory protein troponin switches on and off muscle contraction. In skeletal troponin binding of calcium to sites I and II of the TnC subunit results in a set of structural changes in the troponin complex, displaces tro...

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Detalhes bibliográficos
Main Authors: Genchev, Georgi Z., Kobayashi, Tomoyoshi, Lu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598806/
https://ncbi.nlm.nih.gov/pubmed/23554884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058313
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