Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics

BACKGROUND: The development of resistance to chemotherapies represents a significant barrier to successful cancer treatment. Resistance mechanisms are complex, can involve diverse and often unexpected cellular processes, and can vary with both the underlying genetic lesion and the origin or type of...

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Detalhes bibliográficos
Main Authors: Chen, Li, Stuart, Lynda, Ohsumi, Toshiro K, Burgess, Shawn, Varshney, Gaurav K, Dastur, Anahita, Borowsky, Mark, Benes, Cyril, Lacy-Hulbert, Adam, Schmidt, Emmett V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598783/
https://ncbi.nlm.nih.gov/pubmed/23442791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-93
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