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Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential.
vav, a novel human oncogene, was originally generated in vitro by replacement of its normal 5' coding sequences with sequences from pSV2neo DNA, cotransfected as a selectable marker (S. Katzav, D. Martin-Zanca, and M. Barbacid, EMBO J. 8:2283-2290, 1989). The vav proto-oncogene is normally expr...
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| I publikationen: | Mol Cell Biol |
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| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
1991
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.1912 |
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