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Cannabinoid receptor type 2 (CB2)-selective N-aryl-oxadiazolyl-propionamides: synthesis, radiolabelling, molecular modelling and biological evaluation

BACKGROUND: The endocannabinoid system is involved in many physiological and pathological processes. Two receptors (cannabinoid receptor type 1 (CB1) and type 2 (CB2)) are known so far. Many unwanted psychotic side effects of inhibitors of this system can be addressed to the interaction with CB1. Wh...

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Autori principali: Rühl, Thomas, Deuther-Conrad, Winnie, Fischer, Steffen, Günther, Robert, Hennig, Lothar, Krautscheid, Harald, Brust, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598492/
https://ncbi.nlm.nih.gov/pubmed/23067874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-2858-2-32
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