Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein.

The p21ras GTPase-activating protein (GAP) down-regulates p21ras by stimulating its intrinsic GTPase activity. GAP is found predominantly as a monomer in the cytosol of normal cells. However, in cells expressing an activated cytoplasmic protein-tyrosine kinase, p60v-src, or stimulated with epidermal...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Moran, M F, Polakis, P, McCormick, F, Pawson, T, Ellis, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359849/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.1804-1812.1991
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