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Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein.

The p21ras GTPase-activating protein (GAP) down-regulates p21ras by stimulating its intrinsic GTPase activity. GAP is found predominantly as a monomer in the cytosol of normal cells. However, in cells expressing an activated cytoplasmic protein-tyrosine kinase, p60v-src, or stimulated with epidermal...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Moran, M F, Polakis, P, McCormick, F, Pawson, T, Ellis, C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1991
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.1804
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