Characterization of a tumor necrosis factor-responsive element which down-regulates the human osteocalcin gene.
Tumor necrosis factor (TNF) down-regulates the production of bone matrix proteins by osteoblasts, thereby inhibiting bone formation. Osteocalcin, the major noncollagenous protein in bone, is inhibited by TNF at the transcriptional level. Mapping studies were undertaken to characterize the TNF-respon...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3714-3721.1993 |
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