Characterization of a tumor necrosis factor-responsive element which down-regulates the human osteocalcin gene.

Tumor necrosis factor (TNF) down-regulates the production of bone matrix proteins by osteoblasts, thereby inhibiting bone formation. Osteocalcin, the major noncollagenous protein in bone, is inhibited by TNF at the transcriptional level. Mapping studies were undertaken to characterize the TNF-respon...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Li, Y P, Stashenko, P
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3714-3721.1993
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