Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion

BACKGROUND: Concussions account for the majority of traumatic brain injuries (TBI) and can result in cumulative damage, neurodegeneration, and chronic neurological abnormalities. The underlying mechanisms of these detrimental effects remain poorly understood and there are presently no specific treat...

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Bibliografiske detaljer
Main Authors: Shultz, Sandy R, Bao, Feng, Weaver, Lynne C, Cain, Donald P, Brown, Arthur
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598378/
https://ncbi.nlm.nih.gov/pubmed/23414334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-26
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