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Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion

BACKGROUND: Concussions account for the majority of traumatic brain injuries (TBI) and can result in cumulative damage, neurodegeneration, and chronic neurological abnormalities. The underlying mechanisms of these detrimental effects remain poorly understood and there are presently no specific treat...

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Detalhes bibliográficos
Main Authors: Shultz, Sandy R, Bao, Feng, Weaver, Lynne C, Cain, Donald P, Brown, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598378/
https://ncbi.nlm.nih.gov/pubmed/23414334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-26
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