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Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb development

Talipes equinovarus is one of the most common congenital musculoskeletal anomalies and has a worldwide incidence of 1 in 1000 births. A genetic predisposition to talipes equinovarus is evidenced by the high concordance rate in twin studies and the increased risk to first-degree relatives. Despite th...

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Detaylı Bibliyografya
Asıl Yazarlar: Alvarado, David M, Buchan, Jillian G, Frick, Steven L, Herzenberg, John E, Dobbs, Matthew B, Gurnett, Christina A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598331/
https://ncbi.nlm.nih.gov/pubmed/22892537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.177
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