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Copy number analysis of 413 isolated talipes equinovarus patients suggests role for transcriptional regulators of early limb development

Talipes equinovarus is one of the most common congenital musculoskeletal anomalies and has a worldwide incidence of 1 in 1000 births. A genetic predisposition to talipes equinovarus is evidenced by the high concordance rate in twin studies and the increased risk to first-degree relatives. Despite th...

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Detalhes bibliográficos
Main Authors: Alvarado, David M, Buchan, Jillian G, Frick, Steven L, Herzenberg, John E, Dobbs, Matthew B, Gurnett, Christina A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598331/
https://ncbi.nlm.nih.gov/pubmed/22892537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.177
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