A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

Emerging evidence points to aberrant regulation of translation as a driver of cell transformation in cancer. Given the direct control of translation by tRNA modifications, tRNA modifying enzymes may function as regulators of cancer progression. Here, we show that a tRNA methyltransferase 9-like (hTR...

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Detalhes bibliográficos
Main Authors: Begley, Ulrike, Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Patil, Ashish, Endres, Lauren, Estrada, Yeriel, Chan, Clement TY, Su, Dan, Dedon, Peter C, Aguirre-Ghiso, Julio A, Begley, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598078/
https://ncbi.nlm.nih.gov/pubmed/23381944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201161
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