Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

Nuclear factor kappa B (NF-kappa B) is a critical regulator of several genes which are involved in immune and inflammation responses. NF-kappa B, consisting of a 50-kDa protein (p50) and a 65-kDa protein (p65), is bound to a cytoplasmic retention protein called I kappa B. Stimulation of cells with a...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Beg, A A, Finco, T S, Nantermet, P V, Baldwin, A S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3301-3310.1993
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