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Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis and steatosis

MIF, a multi-potent protein that exhibits both cytokine and chemotactic properties, is expressed by many cell types, including hepatocytes and non-parenchymal cells. We hypothesized that MIF is a key contributor to liver injury after ethanol exposure. Female C57BL/6 or MIF−/− mice were fed an ethano...

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Autores principales: Barnes, Mark A., McMullen, Megan R., Roychowdhury, Sanjoy, Pisano, Sorana G., Liu, Xiuli, Stavitsky, Abram B., Bucala, Richard, Nagy, Laura E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597752/
https://ncbi.nlm.nih.gov/pubmed/23174952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26169
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