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Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors.

We have functionally characterized an enhancer element (kappa E3') which lies 8.5 kb downstream of the immunoglobulin kappa gene. The activity of this enhancer is developmentally controlled. It is inactive at the pre-B-cell stage but active at the B-cell and plasma cell stages. This enhancer is also...

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Publicat a:Mol Cell Biol
Autors principals: Pongubala, J M, Atchison, M L
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899281/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.2.1040-1047.1991
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