Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

The heterogeneous collection of nucleosome remodelling and deacetylation (NuRD) complexes can be grouped into the MBD2- or MBD3-containing complexes MBD2–NuRD and MBD3–NuRD. MBD2 is known to bind to methylated CpG sequences in vitro in contrast to MBD3. Although functional differences have been desc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Günther, Katharina, Rust, Mareike, Leers, Joerg, Boettger, Thomas, Scharfe, Maren, Jarek, Michael, Bartkuhn, Marek, Renkawitz, Rainer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Gene Regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597697/
https://ncbi.nlm.nih.gov/pubmed/23361464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt035
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