Molecular paleontology: a biochemical model of the ancestral ribosome

Ancient components of the ribosome, inferred from a consensus of previous work, were constructed in silico, in vitro and in vivo. The resulting model of the ancestral ribosome presented here incorporates ∼20% of the extant 23S rRNA and fragments of five ribosomal proteins. We test hypotheses that an...

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Bibliografske podrobnosti
Main Authors: Hsiao, Chiaolong, Lenz, Timothy K., Peters, Jessica K., Fang, Po-Yu, Schneider, Dana M., Anderson, Eric J., Preeprem, Thanawadee, Bowman, Jessica C., O'Neill, Eric B., Lie, Lively, Athavale, Shreyas S., Gossett, J. Jared, Trippe, Catherine, Murray, Jason, Petrov, Anton S., Wartell, Roger M., Harvey, Stephen C., Hud, Nicholas V., Dean Williams, Loren
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597689/
https://ncbi.nlm.nih.gov/pubmed/23355613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt023
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