Molecular paleontology: a biochemical model of the ancestral ribosome

Ancient components of the ribosome, inferred from a consensus of previous work, were constructed in silico, in vitro and in vivo. The resulting model of the ancestral ribosome presented here incorporates ∼20% of the extant 23S rRNA and fragments of five ribosomal proteins. We test hypotheses that an...

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Autori principali: Hsiao, Chiaolong, Lenz, Timothy K., Peters, Jessica K., Fang, Po-Yu, Schneider, Dana M., Anderson, Eric J., Preeprem, Thanawadee, Bowman, Jessica C., O'Neill, Eric B., Lie, Lively, Athavale, Shreyas S., Gossett, J. Jared, Trippe, Catherine, Murray, Jason, Petrov, Anton S., Wartell, Roger M., Harvey, Stephen C., Hud, Nicholas V., Dean Williams, Loren
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2013
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597689/
https://ncbi.nlm.nih.gov/pubmed/23355613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt023
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