Molecular paleontology: a biochemical model of the ancestral ribosome

Ancient components of the ribosome, inferred from a consensus of previous work, were constructed in silico, in vitro and in vivo. The resulting model of the ancestral ribosome presented here incorporates ∼20% of the extant 23S rRNA and fragments of five ribosomal proteins. We test hypotheses that an...

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Detalhes bibliográficos
Main Authors: Hsiao, Chiaolong, Lenz, Timothy K., Peters, Jessica K., Fang, Po-Yu, Schneider, Dana M., Anderson, Eric J., Preeprem, Thanawadee, Bowman, Jessica C., O'Neill, Eric B., Lie, Lively, Athavale, Shreyas S., Gossett, J. Jared, Trippe, Catherine, Murray, Jason, Petrov, Anton S., Wartell, Roger M., Harvey, Stephen C., Hud, Nicholas V., Dean Williams, Loren
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597689/
https://ncbi.nlm.nih.gov/pubmed/23355613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt023
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