Expanded target and cofactor repertoire for the transcriptional activator LysM from Sulfolobus

Previously, Lrp-like transcriptional regulator LysM from the hyperthermoacidophilic crenarchaeon Sulfolobus solfataricus was proposed to have a single target, the lysWXJK operon of lysine biosynthesis, and a single effector molecule, l-lysine. Here we identify ∼70 novel binding sites for LysM in the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Song, Ningning, Nguyen Duc, Trong, van Oeffelen, Liesbeth, Muyldermans, Serge, Peeters, Eveline, Charlier, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Gene Regulation, Chromatin and Epigenetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597687/
https://ncbi.nlm.nih.gov/pubmed/23355617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt021
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