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Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity

Maintenance of genomic integrity is essential to ensure normal organismal development and to prevent diseases such as cancer. Nuclear DNA is packaged into chromatin, and thus genome maintenance can be influenced by distinct chromatin environments. In particular, post-translational modifications of h...

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Detalhes bibliográficos
Main Authors: Jørgensen, Stine, Schotta, Gunnar, Sørensen, Claus Storgaard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597678/
https://ncbi.nlm.nih.gov/pubmed/23345616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt012
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