TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes

Unusually for a eukaryote, Trypanosoma brucei transcribes its variant surface glycoprotein (VSG) gene expression sites (ESs) in a monoallelic fashion using RNA polymerase I (Pol I). It is still unclear how ES transcription is controlled in T. brucei. Here, we show that the TDP1 architectural chromat...

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Bibliographic Details
Main Authors: Narayanan, Mani Shankar, Rudenko, Gloria
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597664/
https://ncbi.nlm.nih.gov/pubmed/23361461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1469
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