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Spontaneous telomere to telomere fusions occur in unperturbed fission yeast cells
Telomeres protect eukaryotic chromosomes from illegitimate end-to-end fusions. When this function fails, dicentric chromosomes are formed, triggering breakage-fusion-bridge cycles and genome instability. How efficient is this protection mechanism in normal cells is not fully understood. We created a...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597658/ https://ncbi.nlm.nih.gov/pubmed/23335786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1459 |
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