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Bioengineered 3D Human Kidney Tissue, a Platform for the Determination of Nephrotoxicity

The staggering cost of bringing a drug to market coupled with the extremely high failure rate of prospective compounds in early phase clinical trials due to unexpected human toxicity makes it imperative that more relevant human models be developed to better predict drug toxicity. Drug–induced nephro...

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Autori principali: DesRochers, Teresa M., Suter, Laura, Roth, Adrian, Kaplan, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597621/
https://ncbi.nlm.nih.gov/pubmed/23516613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059219
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