Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.

GTPase-activating protein (GAP) is a cytosolic protein that stimulates the rate of hydrolysis of GTP (GTP to GDP) bound to normal p21ras, but does not catalyze the hydrolysis of GTP bound to oncogenic, activated forms of the ras protein. Transformation of cells with v-src or activated transforming v...

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Sonraí Bibleagrafaíochta
Main Authors: Bouton, A H, Kanner, S B, Vines, R R, Wang, H C, Gibbs, J B, Parsons, J T
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1991
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC359756/
https://ncbi.nlm.nih.gov/pubmed/1703633
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