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Th2 Cell-Intrinsic Hypo-Responsiveness Determines Susceptibility to Helminth Infection

The suppression of protective Type 2 immunity is a principal factor driving the chronicity of helminth infections, and has been attributed to a range of Th2 cell-extrinsic immune-regulators. However, the intrinsic fate of parasite-specific Th2 cells within a chronic immune down-regulatory environmen...

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Detalhes bibliográficos
Main Authors: van der Werf, Nienke, Redpath, Stephen A., Azuma, Miyuki, Yagita, Hideo, Taylor, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597521/
https://ncbi.nlm.nih.gov/pubmed/23516361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003215
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