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Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITRL co-stimulation in vivo(1)
The immune suppression that characterizes human helminth infections can hinder the development of protective immunity or help reduce pathogenic inflammation. Signaling through the T cell co-stimulator GITR counteracts immune down-regulation by augmenting effector T cell responses and abrogating supp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407370/ https://ncbi.nlm.nih.gov/pubmed/21705620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100834 |
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