Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

Seasonal epidemics of influenza virus result in ∼36,000 deaths annually in the United States. Current vaccines against influenza virus elicit an antibody response specific for the envelope glycoproteins. However, high mutation rates result in the emergence of new viral serotypes, which elude neutral...

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Detalhes bibliográficos
Main Authors: Laidlaw, Brian J., Decman, Vilma, Ali, Mohammed-Alkhatim A., Abt, Michael C., Wolf, Amaya I., Monticelli, Laurel A., Mozdzanowska, Krystyna, Angelosanto, Jill M., Artis, David, Erikson, Jan, Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597515/
https://ncbi.nlm.nih.gov/pubmed/23516357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003207
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