Crif1 Deficiency Reduces Adipose OXPHOS Capacity and Triggers Inflammation and Insulin Resistance in Mice

Impaired mitochondrial oxidative phosphorylation (OXPHOS) has been proposed as an etiological mechanism underlying insulin resistance. However, the initiating organ of OXPHOS dysfunction during the development of systemic insulin resistance has yet to be identified. To determine whether adipose OXPH...

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Autores principales: Ryu, Min Jeong, Kim, Soung Jung, Kim, Yong Kyung, Choi, Min Jeong, Tadi, Surendar, Lee, Min Hee, Lee, Seong Eun, Chung, Hyo Kyun, Jung, Saet Byel, Kim, Hyun-Jin, Jo, Young Suk, Kim, Koon Soon, Lee, Sang-Hee, Kim, Jin Man, Kweon, Gi Ryang, Park, Ki Cheol, Lee, Jung Uee, Kong, Young Yun, Lee, Chul-Ho, Chung, Jongkyeong, Shong, Minho
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597503/
https://ncbi.nlm.nih.gov/pubmed/23516375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003356
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