Crif1 Deficiency Reduces Adipose OXPHOS Capacity and Triggers Inflammation and Insulin Resistance in Mice

Impaired mitochondrial oxidative phosphorylation (OXPHOS) has been proposed as an etiological mechanism underlying insulin resistance. However, the initiating organ of OXPHOS dysfunction during the development of systemic insulin resistance has yet to be identified. To determine whether adipose OXPH...

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Huvudupphovsmän: Ryu, Min Jeong, Kim, Soung Jung, Kim, Yong Kyung, Choi, Min Jeong, Tadi, Surendar, Lee, Min Hee, Lee, Seong Eun, Chung, Hyo Kyun, Jung, Saet Byel, Kim, Hyun-Jin, Jo, Young Suk, Kim, Koon Soon, Lee, Sang-Hee, Kim, Jin Man, Kweon, Gi Ryang, Park, Ki Cheol, Lee, Jung Uee, Kong, Young Yun, Lee, Chul-Ho, Chung, Jongkyeong, Shong, Minho
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597503/
https://ncbi.nlm.nih.gov/pubmed/23516375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003356
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