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DNA Topoisomerase III Localizes to Centromeres and Affects Centromeric CENP-A Levels in Fission Yeast

Centromeres are specialized chromatin regions marked by the presence of nucleosomes containing the centromere-specific histone H3 variant CENP-A, which is essential for chromosome segregation. Assembly and disassembly of nucleosomes is intimately linked to DNA topology, and DNA topoisomerases have p...

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Autors principals: Norman-Axelsson, Ulrika, Durand-Dubief, Mickaël, Prasad, Punit, Ekwall, Karl
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597498/
https://ncbi.nlm.nih.gov/pubmed/23516381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003371
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