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Matrix Metalloproteinase-28 Deletion Exacerbates Cardiac Dysfunction and Rupture Following Myocardial Infarction in Mice by Inhibiting M2 Macrophage Activation

RATIONALE: Matrix metalloproteinase (MMP)-28 regulates the inflammatory and extracellular matrix (ECM) responses in cardiac aging, but the roles of MMP-28 after myocardial infarction (MI) have not been explored. OBJECTIVE: To determine the impact of MMP-28 deletion on post-MI remodeling of the left...

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Detalhes bibliográficos
Main Authors: Ma, Yonggang, Halade, Ganesh V., Zhang, Jianhua, Ramirez, Trevi A., Levin, Daniel, Voorhees, Andrew, Jin, Yu-Fang, Han, Hai-Chao, Manicone, Anne M., Lindsey, Merry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597388/
https://ncbi.nlm.nih.gov/pubmed/23261783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.300502
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