Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia

The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary pacemaker of the heart. Abnormalities in the development of the SAN can result in irregular heart rates (arrhythmias). Although several of the critical genes important for SAN form...

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Bibliographische Detailangaben
Hauptverfasser: Hoffmann, Sandra, Berger, Ina M., Glaser, Anne, Bacon, Claire, Li, Li, Gretz, Norbert, Steinbeisser, Herbert, Rottbauer, Wolfgang, Just, Steffen, Rappold, Gudrun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2013
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Original Contribution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597335/
https://ncbi.nlm.nih.gov/pubmed/23455426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0339-z
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