Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia

The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary pacemaker of the heart. Abnormalities in the development of the SAN can result in irregular heart rates (arrhythmias). Although several of the critical genes important for SAN form...

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Autors principals: Hoffmann, Sandra, Berger, Ina M., Glaser, Anne, Bacon, Claire, Li, Li, Gretz, Norbert, Steinbeisser, Herbert, Rottbauer, Wolfgang, Just, Steffen, Rappold, Gudrun
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2013
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Original Contribution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597335/
https://ncbi.nlm.nih.gov/pubmed/23455426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0339-z
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