Bioanalytical method validation of rapamycin in ocular matrix by QTRAP LC–MS/MS: Application to rabbit anterior tissue distribution by topical administration of rapamycin nanomicellar formulation

A novel, fast and sensitive 3200 QTRAP LC–MS/MS method was validated for rapamycin analysis in the rabbit eye following 0.2% administration of nanomicellar eye drop formulation. The LC–MS/MS technique was developed with electrospray ionization (ESI) in positive mode. Rapamycin was extracted from ind...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Earla, Ravinder, Cholkar, Kishore, Gundaaa, Sriram, Earla, Rajya Lakshmi, Mitra, Ashim K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597233/
https://ncbi.nlm.nih.gov/pubmed/23122404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2012.09.014
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky