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Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK

Galangin, an active flavonoid present at high concentration in Alpinia officinarum Hance and propolis, shows cytotoxicity towards several cancer cell lines, including melanoma. However, the specific cellular targets of galangin-induced cytotoxicity in melanoma are still unknown. Here, we investigate...

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Bibliografiske detaljer
Main Authors: Zhang, Wenjing, Lan, Yan, Huang, Qilai, Hua, Zichun
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597176/
https://ncbi.nlm.nih.gov/pubmed/23001390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-012-9499-1
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