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Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK

Galangin, an active flavonoid present at high concentration in Alpinia officinarum Hance and propolis, shows cytotoxicity towards several cancer cell lines, including melanoma. However, the specific cellular targets of galangin-induced cytotoxicity in melanoma are still unknown. Here, we investigate...

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Detalhes bibliográficos
Main Authors: Zhang, Wenjing, Lan, Yan, Huang, Qilai, Hua, Zichun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597176/
https://ncbi.nlm.nih.gov/pubmed/23001390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-012-9499-1
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