MKK6 Phosphorylation Regulates Production of Superoxide by Enhancing Rac GTPase Activity

Rac-dependent NADPH oxidases generate reactive oxygen species used in cell signaling and microbial killing or both. Whereas the mechanisms leading to NADPH oxidase activation are fairly well studied, the mechanisms that control downregulation of this enzyme complex remain unclear. We hypothesized th...

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Bibliographic Details
Main Authors: HARRAZ, MAGED M., PARK, ANDREA, ABBOTT, DUANE, ZHOU, WEIHONG, ZHANG, YULONG, ENGELHARDT, JOHN F.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597076/
https://ncbi.nlm.nih.gov/pubmed/17854274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2007.1579
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