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Structural basis for duplex RNA recognition and cleavage by Archaeoglobus fulgidus C3PO

Oligomeric complexes of Trax and Translin proteins, known as C3POs, participate in a variety of eukaryotic nucleic acid metabolism pathways including RNAi and tRNA processing. In RNAi in humans and Drosophila, C3PO activates pre-RISC by removing the passenger strand of the siRNA precursor duplex usi...

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Autori principali: Parizotto, Eneida A, Lowe, Edward D, Parker, James S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597040/
https://ncbi.nlm.nih.gov/pubmed/23353787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2487
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