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Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord
Cell fate specification in the CNS is controlled by the secreted morphogen sonic hedgehog (Shh). At spinal cord levels, Shh produced by both the notochord and floor plate (FP) diffuses dorsally to organize patterned gene expression in dividing neural and glial progenitors. Despite the fact that two...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Company of Biologists
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596997/ https://ncbi.nlm.nih.gov/pubmed/23482494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.090845 |
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