The vascular permeabilizing factors histamine and serotonin induce angiogenesis through TR3/Nur77 and subsequently truncate it through thrombospondin-1

Angiogenesis plays an important role in cancer and in many other human diseases. Vascular endothelial growth factor-A (VEGF-A), the best known angiogenic factor, was originally discovered as a potent vascular permeability factor (VPF), suggesting that other vascular permeabilizing agents, such as hi...

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Bibliographic Details
Main Authors: Qin, Liuliang, Zhao, Dezheng, Xu, Jianfeng, Ren, Xianghui, Terwilliger, Ernest F., Parangi, Sareh, Lawler, Jack, Dvorak, Harold F., Zeng, Huiyan
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596973/
https://ncbi.nlm.nih.gov/pubmed/23315169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-443903
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