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The function of hematopoietic stem cells is altered by both genetic and inflammatory factors in lupus mice
Hematopoietic stem cells (HSCs) are protected in a metabolically dormant state within the bone marrow stem cell niche. Inflammation has been shown to disrupt HSC dormancy and cause multiple functional changes. Here, we investigated whether HSC functions were altered in systemic lupus erythematosus (...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596961/ https://ncbi.nlm.nih.gov/pubmed/23315165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-433755 |
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