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Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis.

The hematopoietic-specific DNA-binding protein B1 binds to the DNA consensus sequence AAAGRGGAARYG located twice in intervening sequence 2 of both of the mouse beta-globin genes (D. L. Galson and D.E. Housman, Mol. Cell. Biol. 8:381-392, 1988). B1 was cloned by expression of a murine erythroleukemia...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Galson, D L, Hensold, J O, Bishop, T R, Schalling, M, D'Andrea, A D, Jones, C, Auron, P E, Housman, D E
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359686/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8474451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.5.2929-2941.1993
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