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Impact of Mast Cell Chymase on Renal Disease Progression

Chymase, a serine protease found in mast cell granules, is released into the interstitium following injury or inflammation. Chymase is the primary ACE-independent pathway of angiotensin II formation, and also functions to activate TGF-beta and other promoters of extracellular matrix degradation, the...

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Detalhes bibliográficos
Main Authors: Wasse, Haimanot, Naqvi, Nawazish, Husain, Ahsan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596835/
https://ncbi.nlm.nih.gov/pubmed/23503162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157340212800505007
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