Oral Administration of an Angiotensin-Converting Enzyme 2 Activator Ameliorates Diabetes-Induced Cardiac Dysfunction

We evaluated the hypothesis that activation of endogenous angiotensin-converting enzyme (ACE) 2 would improve cardiac dysfunction induced by diabetes. Ten days after diabetes induction (streptozotocin, 50mg/kg, i.v.), male Wistar rats were treated with the ACE2 activator 1-[[2-(dimethylamino)ethyl]a...

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Main Authors: Murça, Tatiane M., Moraes, Patrícia L., Capuruço, Carolina A.B., Santos, Sérgio H.S., Melo, Marcos B., Santos, Robson A.S., Shenoy, Vinayak, Katovich, Michael J., Raizada, Mohan K., Ferreira, Anderson J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596786/
https://ncbi.nlm.nih.gov/pubmed/22595130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2012.05.093
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