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Repair of deletions and double-strand gaps by homologous recombination in a mammalian in vitro system.

We have designed an in vitro system using mammalian nuclear extracts, or fractions derived from them, that can restore the sequences missing at double-strand breaks (gaps) or in deletions. The recombination substrates consist of (i) recipient DNA, pSV2neo with gaps or deletions ranging from 70 to 39...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Jessberger, R, Berg, P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1991
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.445-457.1991
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