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TREM2 is associated with risk of Alzheimer disease in Spanish population

Two recent studies have reported the association of rs75932628-T in the TREM2 gene with risk for Alzheimer’s disease (AD). Rs75932628-T is a rare non-synonymous variant (p. R47H) that confers a high risk of AD with an effect size similar to that of the APOE ε4 allele. However, this association has n...

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Hlavní autoři: Benitez, BA, B, Cooper, P, Pastor, Jin, SC, S, Cervantes, E, Lorenzo, C, Cruchaga
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596468/
https://ncbi.nlm.nih.gov/pubmed/23391427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.12.018
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