Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model

BACKGROUND: Autism spectrum disorders (ASDs) are caused by both genetic and environmental factors. Mitochondria act to connect genes and environment by regulating gene-encoded metabolic networks according to changes in the chemistry of the cell and its environment. Mitochondrial ATP and other metabo...

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Autori principali: Naviaux, Robert K., Zolkipli, Zarazuela, Wang, Lin, Nakayama, Tomohiro, Naviaux, Jane C., Le, Thuy P., Schuchbauer, Michael A., Rogac, Mihael, Tang, Qingbo, Dugan, Laura L., Powell, Susan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596371/
https://ncbi.nlm.nih.gov/pubmed/23516405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057380
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