Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model

BACKGROUND: This study was designed to test a new approach to drug treatment of autism spectrum disorders (ASDs) in the Fragile X (Fmr1) knockout mouse model. METHODS: We used behavioral analysis, mass spectrometry, metabolomics, electron microscopy, and western analysis to test the hypothesis that...

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Detalles Bibliográficos
Publicado en:Mol Autism
Autores principales: Naviaux, Jane C, Wang, Lin, Li, Kefeng, Bright, A Taylor, Alaynick, William A, Williams, Kenneth R, Powell, Susan B, Naviaux, Robert K
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334917/
https://ncbi.nlm.nih.gov/pubmed/25705365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-6-1
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