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Computer-Aided Design of Fragment Mixtures for NMR-Based Screening

Fragment-based drug discovery is widely applied both in industrial and in academic screening programs. Several screening techniques rely on NMR to detect binding of a fragment to a target. NMR-based methods are among the most sensitive techniques and have the further advantage of yielding a low rate...

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Detalhes bibliográficos
Main Authors: Arroyo, Xavier, Goldflam, Michael, Feliz, Miguel, Belda, Ignasi, Giralt, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596306/
https://ncbi.nlm.nih.gov/pubmed/23516512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058571
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