Pathology Associated with AAV Mediated Expression of Beta Amyloid or C100 in Adult Mouse Hippocampus and Cerebellum

Accumulation of beta amyloid (Aβ) in the brain is a primary feature of Alzheimer’s disease (AD) but the exact molecular mechanisms by which Aβ exerts its toxic actions are not yet entirely clear. We documented pathological changes 3 and 6 months after localised injection of recombinant, bi-cistronic...

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Detaylı Bibliyografya
Asıl Yazarlar: Drummond, Eleanor S., Muhling, Jill, Martins, Ralph N., Wijaya, Linda K., Ehlert, Erich M., Harvey, Alan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596293/
https://ncbi.nlm.nih.gov/pubmed/23516609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059166
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